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. 2018 May 8;63(3):989–1002. doi: 10.3233/JAD-180059

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Fig.2 — The analyses of cerebrospinal fluid markers in the three patient groups. A) pTau was significantly higher in the AD group compared to the iNPH group (p < 0.001), or the CN group (p < 0.001). No significant difference was seen between the iNPH and CN groups. B) Aβ₄₂ was significantly low in the AD group (p = 0.008) and the iNPH group (p = 0.029) compared to the CN group. No significant difference was seen between the AD and iNPH groups. C) Aβ₄₂ toxic conformer was high in the AD group compared to the iNPH group (p = 0.006), compared to the CN group (p < 0.001). No significant difference was seen between the iNPH and CN groups. D) Aβ₄₂ toxic conformer ratio, indicating the percentage of Aβ₄₂ toxic conformer to total Aβ₄₂, was highest in the AD group, followed by the iNPH group, and lowest in the CN group (AD versus iNPH: p = 0.002; iNPH versus CN: p = 0.001; AD versus CN: p < 0.001).