Table 2.
Characteristics of the possible iNPH patients
| All | Analyzed total (low + high) | Low-pTau | High-pTau | Low- versus High-pTau | Pre- versus postoperative | |
| Patients: number (%) | 51 | 38 (75%) | 27 (71%) | 11 (29%) | ||
| Age: mean ± SD | 73.8 ± 6.4 | 76.9 ± 3.5 | 76.5 ± 3.5 | 77.9 ± 3.3 | 0.141 | |
| Sex: Male (number (%)) | 36 (71%) | 25 (66%) | 15 (56%) | 10 (91%) | *0.03 | |
| DESH: number/total number (%) | 45 (88%) | 34/37 (92%) | 24/26 (92%) | 10/11 (91%) | 0.636 | |
| Tap-test: number of positive/total number (%) | 35 (78%) | 26/34 (76%) | 18/24 (75%) | 8/10 (80%) | 0.754 | |
| White matter change: number of ARWMC score 0-1/total number (%) | 32 (63%) | 23/38 (61%) | 15/27 (56%) | 8/11 (73%) | 0.661 | |
| Evans Index: mean ± SD | ||||||
| preoperative | 0.34 ± 0.03 | 0.34 ± 0.031 | 0.33 ± 0.033 | 0.206 | 1 versus 2: *0.022 | |
| postoperative | 0.32 ± 0.03 | 0.32 ± 0.042 | 0.31 ± 0.044 | 0.430 | 3 versus 4: 0.244 | |
| Comorbidities: number/total number (%) | ||||||
| Hypertension | 28 (55%) | 22/36 (61%) | 14/25 (56%) | 8/11 (73%) | 0.343 | |
| Diabetes | 10 (21%) | 7/35 (20%) | 5/25 (20%) | 2/10 (20%) | 1.000 | |
| Dyslipidemia | 19 (40%) | 15/35 (43%) | 12/25 (48%) | 3/10 (30%) | 0.331 | |
| Cardiac diseases | 1 (2%) | 0/38 (0%) | 0/23 (0%) | 0/15 (0%) | NA | |
| Stroke | 5 (10%) | 3/38 (8%) | 3/27 (11%) | 0/11 (0%) | 0.249 | |
| Medication for dementia: number/total number (%) | ||||||
| preoperative | 9 (18%) | 7/38 (18%) | 3/27 (11%)5 | 4/11 (36%)6 | 0.069 | 5 versus 6: **0.006 |
Values are shown as number or mean ± SD. Mann-Whitney U tests were conducted for age, and Evans index and Pearson’s chi-squared test for all other domains. *p < 0.05 and **p < 0.01 were considered to be statistically significant. DESH, Disproportionately enlarged subarachnoid-space hydrocephalus; ARWMC, Age-related white matter change.