Fig.2.

Representative deconvoluted mass spectra from controls (healthy age-matched donors) and Alzheimer’s disease (AD) patients (in both plasma and cerebrospinal fluid [CSF]). In addition to the native albumin (Alb-SH), cysteinylation of the Cys34 residue (Alb+Cys) and sulfinylation of the Cys34 residue (Alb+SO₂H); the following structural alterations were detected: truncation of the last two aminoacid residues at the N-terminal (Alb-DA); glycation (Alb+Glyc) and the sulfonylation of the Cys34 residue (Alb+SO₃H).