Fig.4.

MS results of representative albumin oxidation forms (Alb-SH, Alb+Cys, and Alb+SO₂H) in plasma and cerebrospinal fluid (CSF) from controls (healthy age-matched donors) and Alzheimer’s disease (AD) patients. The subfigures show relative intensities (% ) of the native albumin (Alb-SH) (a), the cysteinylation of the Cys34 residue (Alb+Cys) (b), and sulfinylation of the Cys34 residue (Alb+SO₂H) (c). Data are shown as median±interquartile range. Unpaired t test: ( ^****p < 0.0001; AD versus Control); Paired t test: ( ^# # # # p < 0.0001; AD CSF versus AD Plasma).