Average platinum concentrations in tumor, kidney and liver samples of treated mice determined by ICP-MS (values are presented as mean ± standard deviation; i.p. - intraperitoneal, i.v. - intravenous).
Compound | Route of admin. | Pt concentration [μg g−1] | ||
---|---|---|---|---|
Tumor | Kidney | Liver | ||
1a | i.p. | 1.29 ± 0.24 | 8.15 ± 0.38 | 12.35 ± 1.47 |
2 | i.v. | 4.05 ± 0.32 | 4.87 ± 0.45 | 3.20 ± 0.13 |
Cisplatin | i.v. | 0.25 ± 0.05 | 1.67 ± 0.36 | 1.26 ± 0.15 |
Data taken from ref. 7.