Fig.5.

Effect of LC on serum and cardiac muscle levels of TNF-α and IL-1ß of HF/HC diet induced diabetic rats. Rats were fed with regular chow diet (control) or HF/HC diet for 5 weeks (diabetic). HF/HC fed rats were treated with LC (300 mg/kg/day) from the first day of diabetes confirmation for 14 or 28 days (Diabetic+LC, n=5/group). A. Serum TNF-α, B. Cardiac muscle TNF-α, C. Serum IL-1ß, and D. Cardiac muscle IL-1ß. Data are means ± SE. Different letters (a, b and c) demonstrate significant differences between groups in each day at P<0.05.

LC; L-carnitine, HF/HC; High fat/high carbohydrate, TNF-α; Tumor necrosis factor-α, and IL-1ß; interleukin-1ß.