Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 23;77(7):598–607. doi: 10.1093/jnen/nly035

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 American Association of Neuropathologists, Inc.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

FIGURE 3. — Quantification of Iba-1, CX3CL1, and CX3CR1 protein expression in MSA. (A) Representative Western immunoblots in control [C] and MSA [M] frontal cortex. (B) No significant alteration was detected in the expression of Iba-1 in MSA compared with control. CX3CL1 was detected at the predicted molecular weight of ∼100 kDa (A), which showed a trend toward upregulation without significance (C). The lower molecular weight band representing the soluble form of the protein was detected at 60 kDa (A) and was significantly decreased in MSA when normalized to βIII-tubulin (C, p = 0.03). CX3CR1 was detected at the predicted molecular weight of 47 kDa (A) and showed a highly significant increase in expression in MSA brain compared with control when normalized to Iba-1, determined by Student t test of MSA compared with control (C, p = 0.0002).