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. 2018 Jun 4;77(7):628–635. doi: 10.1093/jnen/nly046

FIGURE 1.

FIGURE 1.

Mutation detection in CSF-ctDNA by ddPCR. Representative 2D plots of ddPCR droplet reads. Bottom plot represents droplet reads from a no-template control sample. All droplets are double negative in the no-template control. The top panel represents the droplet reads from the CSF-cfDNA from Patient 4. Note the presence of WT-DNA in the X-axis (green dots) and BRAF p.V600E mutant DNA in the Y-axis (blue dots). A few droplets contained both WT and mutant DNA and fell in the double positive category (orange dots).