Table 4.
Univariate Logistic Regression Models and Multivariate Logistic Regression Model for Acute Human Immunodeficiency Virus (HIV) Infection Versus (HIV) Negative in the Derivation Set (n = 673)
| Symptoms (Yes vs No)a | Univariate Symptom Model | Multivariate Symptom Model | SDSS Point Value | ||
|---|---|---|---|---|---|
| OR (95% CI) | P Value | OR (95% CI) | P Value | ||
| Headache | 3.4 (2.0–5.7) | <.001 | 0.8 (.4–1.7) | .543 | … |
| Pharyngitis | 4.8 (2.9–8.2) | <.001 | 1.9 (.9–3.9) | .077 | … |
| Rash | 3.6 (1.9–7.1) | <.001 | 31.3 (.5–3.4) | .613 | … |
| Myalgia | 16.8 (9.4–30.0) | <.001 | 7.8 (3.3–18.7) | <.001 | 8 |
| Fatigue | 8.7 (5.1–14.8) | <.001 | 0.9 (.4–2.2) | .775 | … |
| Fever | 24.9 (13.7–45.4) | <.001 | 10.9 (4.6–26.0) | <.001 | 11 |
| Night sweats | 10.5 (5.9–18.9) | <.001 | 11.3 (.5–3.4) | .578 | … |
| GI symptomsb | 4.1 (2.4–7.1) | <.001 | 0.6 (.2–1.4) | .22 | … |
| Arthralgia | 8.5 (4.2–17.0) | <.001 | 0.8 (.3–2.4) | 80.678 | … |
| Weight loss ≥2.5 kg | 14.8 (6.3–34.9) | <.001 | 4.1 (1.1–15.1) | .035 | 4 |
| Lymphadenopathy | 5.8 (2.9–11.6) | <.001 | 1.5 (.6–3.9) | .436 | … |
Abbreviations: CI, confidence interval; GI, gastrointestinal; OR, odds ratio; SDSS, San Diego Symptom Score.
aSymptoms present in the 14 days prior to testing day.
bDiarrhea, nausea, vomiting.