Table 5.
Performance Characteristics of Pediatric Infectious Diseases Society–Infectious Diseases Society of America Severity Criteria for Need for Hospitalization
| Variable |
Need for Hospitalization, n = 102
N (%) |
Sensitivity, % | Specificity, % | PPV, % | NPV, % | LR+ | LR− |
|---|---|---|---|---|---|---|---|
| Severe community-acquired pneumonia by Pediatric Infectious Diseases Society– Infectious Diseases Society of America definition | 97 (95.1) | 95 | 16 | 67 | 64 | 1.13 | 0.31 |
| Major Criteria | |||||||
| Mechanical ventilation | 1 (1.0) | 1 | 100 | 100 | 36 | a | 0.99 |
| Fluid refractory shock | 5 (4.9) | 5 | 96 | 71 | 36 | 1.4 | 0.99 |
| NIPPV | 8 (7.8) | 8 | 98 | 89 | 37 | 4.47 | 0.94 |
| Hypoxemia requiring FiO2 more than general hospital unit | 29 (28.4) | 28 | 68 | 62 | 35 | 0.9 | 1.05 |
| Minor Criteria | |||||||
| Respiratory rate greater than World Health Organization criteria | 95 (93.1) | 93 | 14 | 66 | 53 | 1.08 | 0.49 |
| Apnea | 0 (0.0) | 0 | 100 | a | 36 | a | 1 |
| Low SpO2:FiO2 ratio | 2 (2.0) | 2 | 98 | 67 | 36 | 1.13 | 1 |
| Increased work of breathing | 77 (75.5) | 75 | 18 | 62 | 29 | 0.92 | 1.4 |
| Multilobar infiltrates | 69 (67.6) | 68 | 51 | 71 | 47 | 1.38 | 0.64 |
| Altered mental status | 11 (10.8) | 11 | 93 | 73 | 38 | 1.6 | 0.95 |
| Hypotension | 2 (2.0) | 2 | 98 | 67 | 36 | 1.12 | 1 |
| Effusion | 5 (4.9) | 5 | 98 | 83 | 37 | 2.79 | 0.97 |
| Metabolic acidosis | 2 (2.0) | 2 | 98 | 67 | 36 | 1.12 | 1 |
| Pediatric early warning score >6 | 66 (64.7) | 65 | 39 | 65 | 38 | 1.05 | 0.91 |
Abbreviation: LR, likelihood ratio; NIPPV, non-invasive positive pressure ventilation; NPV, negative predictive value; PPV, positive predictive value.
aSample size precludes calculation of these values.