Table 2.
Characteristics of participants included in this study (AFAST offspring, N = 86)
| Variable | Category | Placebo (n = 43) | Folic-acid supplement |
||
|---|---|---|---|---|---|
| 0.2 mg/day (n = 20) | 5 mg/day (n = 23) | ||||
| Categorical | n (%) | n (%) | n (%) | Chi2 | |
| Age at follow-up (years) (N = 86) | 46 | 6 (14.0) | 14 (70.0) | 6 (26.1) | |
| 47 | 33 (76.7) | 6 (30.0) | 17 (73.9) | ||
| 48 | 4 (9.3) | – | – | <0.001 | |
| Current smoking (N = 86) | No | 26 (60.5) | 9 (45) | 14 (60.9) | |
| Yes | 17 (39.5) | 11 (55) | 9 (39.1) | 0.47 | |
| Education (N = 84) | ≤O-level | 19 (46.3) | 10 (50) | 12 (52.2) | |
| A-level/university | 22 (53.7) | 10 (50) | 11 (47.8) | 0.90 | |
| Alcohol intake | Daily/weekly | 19 (44.2) | 12 (60.0) | 12 (52.2) | 0.56 |
| Monthly | 20 (46.5) | 8 (40.0) | 10 (43.5) | ||
| Not at all | 4 (9.30) | 0 (0) | 1 (4.4) | ||
| Folic-acid supplements | Yes | 1 (2.3) | 1 (5.0) | 0 (0) | |
| No | 42 (97.7) | 19 (95.0) | 23 (100) | 0.56 | |
| Current medication | Yes | 31 (72.1) | 15 (75.0) | 17 (73.9) | 0.97 |
| No | 12 (27.9) | 5 (25.0) | 6 (26.1) | ||
| Health problems | Yes | 25 (58.1) | 12 (60.0) | 14 (60.9) | 0.98 |
| No | 18 (41.9) | 8 (40.0) | 9 (39.1) | ||
| Continuous | Mean (SD) | Mean (SD) | Mean (SD) | ANOVA | |
| BMI (kg/m2) (N = 85) | 24.2 (3.8) | 26.5 (6.4) | 27.8 (7.2) | 0.04 | |
| Length of gestation (weeks) (N = 86) | 40.9 (1.1) | 39.9 (2.6) | 40.3 (1.5) | 0.07 | |
| Birthweight (g) (N = 86) | 3333 (506) | 3093 (620) | 3269 (493) | 0.25 | |