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. 2018 Apr 23;77(7):555–566. doi: 10.1093/jnen/nly031

FIGURE 3.

FIGURE 3.

Extracellular matrix composition and thickness of intracranial aneurysm (IA) wall. Thin regions of UR-IAs contain less total collagen than thicker regions (A), whereas total collagen content is not affected by the thickness of the IA wall in the ruptured group (F). Type I (black) and III (grey) collagen relative contributions are significantly different between thick and thin regions of UR-IA domes (B) due to a higher content of type I collagen (C) and a lower content in type III collagen (D) in thin regions. No significant differences have been found for these parameters in R-IAs (G–I). Elastin content is not influenced by the thickness of aneurysmal wall in UR-IA (E) and R-IA (J) domes. Results are shown as individual values and as median ± interquartile range (A, C–F, H–J) or in percentage (B, G). *p < 0.05, **p < 0.01, ***p < 0.001, nonparametric Mann-Whitney U test for comparison of median and Fisher exact test for comparison of distributions.