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. 2018 Apr 23;77(7):555–566. doi: 10.1093/jnen/nly031

FIGURE 6.

FIGURE 6.

Risk factors and aneurysmal wall composition. Spearman correlation between intracranial aneurysm (IA) size and CD68 (A), total collagen (B), and type III collagen (C) contents in UR-IAs. UR-IAs with a rough appearance have a higher content of type III collagen (D) and a lower type I collagen-type III collagen ratio (E) than UR-IA with a smooth appearance (n = 15 and 14, respectively, *p < 0.05, nonparametric Mann-Whitney U test). SMC content is lower in the unruptured aneurysmal wall of smokers (current and former) in comparison to nonsmokers (F, n = 17 for R-IA, n = 21 for UR-IA/smokers, and n = 10 for UR-IA/nonsmokers, *p < 0.05, ***p < 0.001, nonparametric Mann-Whitney U test).