Figure 3.

The single variant shared across the 99%-credible sets of the discovery and replication cohort also has the strongest association in a weighted trans-ancestral meta-analysis. A weighted meta-analysis was performed on the results of the logistic regression modelling of each cohort within the discovery and replication cohort. Each variant is represented as a data point in the context of its genomic location and is colored based on the variant’s inclusion in the AICS analysis (shown in red). Genomic position is provided using GRCh37 coordinates. The only variant shared across the 99%- credible sets (red), rs11889341, shows the strongest association within a trans-ancestral meta-analysis.