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. 2018 Feb 27;47(3):771–779. doi: 10.1093/ije/dyy024

Table 2.

Association of amount of leisure-time physical activity with risk of death from all causes, CVD, cancer and other causes

Total subjects None/almost none (never, or less than 1 h per week) Low (1.0-2.9 h per week) Intermediate (3.0-4.9 h per week) High (5.0 h or more per week) P for trend

All subjects
No. of subjects 467 729 332 829 51 578 32 554 50 768
Total mortality
 No. 65 858 45 963 6940 4625 8330
 HR (95% CI)a 1.00 (reference) 0.85 (0.81-0.90) 0.86 (0.81-0.92) 0.86 (0.82-0.91) < 0.001
CVD mortality
 No. 19 381 13 478 2003 1376 2524
 HR (95% CI)a 1.00 (reference) 0.83 (0.78-0.89) 0.86 (0.78-0.94) 0.84 (0.77-0.92) < 0.001
Cancer mortality
 No. 25 048 17 283 2701 1828 3236
 HR (95% CI)a 1.00 (reference) 0.92 (0.88-0.95) 0.94 (0.87-1.00) 0.93 (0.89-0.98) < 0.001
Other causes
 No. 21 429 15 202 2236 1421 2570
 HR (95% CI)a 1.00 (reference) 0.82 (0.77-0.88) 0.80 (0.76-0.85) 0.80 (0.75-0.86) < 0.001

Excluding first 3 years of follow-up
No. of subjects 453 948 322 806 49 953 31 730 49 459
Total mortality
 No. 57 473 39 890 6142 4108 7333
 HR (95% CI)a 1.00 (reference) 0.87 (0.83-0.92) 0.89 (0.84-0.94) 0.89 (0.85-0.94) < 0.001
CVD mortality
 No. 16 683 11 538 1748 1202 2195
 HR (95% CI)a 1.00 (reference) 0.85 (0.79-0.91) 0.87 (0.79-0.96) 0.87 (0.79-0.96) < 0.001
Cancer mortality
 No. 21 640 14 898 2347 1602 2793
 HR (95% CI)a 1.00 (reference) 0.92 (0.88-0.97) 0.96 (0.90-1.02) 0.96 (0.92-1.00) 0.013
Other causes
 No. 19 150 13 454 2047 1304 2345
 HR (95% CI)a   1.00 (reference) 0.85 (0.79-0.91) 0.83 (0.79-0.88) 0.85 (0.79-0.90) < 0.001
a

The calculations of hazard ratios were adjusted for age, sex, educational level, marital status and smoking pack-years.