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. 2018 Apr 18;29(6):1461–1467. doi: 10.1093/annonc/mdy118

Figure 4.

Figure 4.

Change from baseline to day 15 of COMPOSE-4 in PAC-SYM (A) and PAC-QOL (B) overall scores and scores for each domain [mean (SD); FAS]. *P = 0.045 versus placebo. P = 0.015 versus placebo. FAS, full analysis set; ns, not significant; PAC-QOL, Patient Assessment of Constipation Quality of Life; PAC-SYM, Patient Assessment of Constipation Symptoms; SD, standard deviation.