Figure 3. Research into the connections between epigenetics and disease has greatly increased from 1990–2015.

(A) Yearly number of publications on PubMed matching combinatorial search results of “epigenetics” keywords alone, or paired with “disease” keywords. The following search queries were used for “epigenetics”: (epigenetic OR epigenetics OR epigenome OR “histone modification” OR “DNA methylation” OR “histone methylation” OR “histone acetylation”), and “epigenetics and disease”: (epigenetic OR epigenetics OR epigenome OR “histone modification” OR “DNA methylation” OR “histone methylation” OR “histone acetylation”) AND (disease OR disorder OR cancer OR syndrome). (B) Yearly percentage of epigenetics articles (from A) that involve disease.