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. Author manuscript; available in PMC: 2018 Jun 18.
Published in final edited form as: J Alzheimers Dis Parkinsonism. 2018 Jan 9;8(1):412.

Figure 4. Spatiotemporal evolution of Alzheimer disease across rodent CA1 axes.

Figure 4

In mouse models, Alzheimer disease (AD) pathology begins in ventral hippocampus and progresses dorsally (left) and begins in distal CA1 at the CA1-S border, and progresses proximally to CA2 (right). Distribution across the radial axis is unknown.