Table 3.
Prognostic factors for cancer-specific survival before and after propensity score–matched analysis
| Variable | Before propensity score matching
|
After propensity score matching
|
||||||
|---|---|---|---|---|---|---|---|---|
| Univariate analysis
|
Multivariate analysis
|
Univariate analysis
|
Multivariate analysis
|
|||||
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age, years | ||||||||
| ≤65 | Reference | Reference | Reference | Reference | ||||
| >65 | 1.227 (1.146–1.314) | <0.001 | 1.2280 (1.1455–1.3164) | <0.001 | 1.219 (1.096–1.356) | <0.001 | 1.2028 (1.0793–1.3403) | <0.001 |
| Gender | ||||||||
| Female | Reference | Reference | Reference | Reference | ||||
| Male | 1.118 (1.044–1.197) | 0.0014 | 1.1728 (1.0929–1.2586) | <0.001 | 1.143 (1.029–1.269) | 0.0125 | 1.1463 (1.0280–1.2781) | 0.0139 |
| Race | ||||||||
| White | Reference | Reference | Reference | Reference | ||||
| Black | 1.045 (0.917–1.191) | 0.502 | 1.346 (1.0713–1.692) | 0.0108 | 1.3510 (1.0721–1.7025) | 0.010 | ||
| Other/unknown | 0.9901 (0.893–1.097) | 0.849 | 1.062 (0.9081–1.243) | 0.4495 | 1.0200 (0.8709–1.1946) | 0.806 | ||
| Marital status | ||||||||
| Others | Reference | Reference | Reference | Reference | ||||
| Married | 0.8751 (0.814–0.9408) | <0.001 | 0.8733 (0.8107–0.9408) | <0.001 | 0.8410 (0.7494–0.9437) | 0.0032 | 0.8693 (0.7696–0.9819) | 0.0241 |
| Unknown | 0.7737 (0.632–0.9475) | 0.013 | 0.7753 (0.6326–0.9502) | 0.014 | 0.6415 (0.4496–0.9151) | 0.0143 | 0.6317 (0.4416–0.9036) | 0.0119 |
| Grading | ||||||||
| G1 | Reference | Reference | Reference | Reference | ||||
| G2 | 1.109 (0.944–1.304) | 0.2076 | 1.1407 (0.9699–1.3414) | 0.1115 | 1.213 (0.947–1.554) | 0.1261 | 1.2823 (0.9991–1.6457) | 0.051 |
| G3 | 1.384 (1.176–1.628) | <0.001 | 1.4592 (1.2395–1.7179) | <0.001 | 1.535 (1.205–1.954) | <0.001 | 1.6085 (1.2602–2.053) | <0.001 |
| G4 | 1.796 (1.193–2.705) | 0.00503 | 1.6953 (1.1249–2.5548) | 0.0116 | 1.684 (0.816–3.477) | 0.1584 | 1.4596 (0.7045–3.0239) | 0.3088 |
| Unknown | 1.300 (1.123–1.505) | <0.001 | 1.2790 (1.1044–1.4811) | 0.001 | 1.416 (1.134–1.766) | 0.0021 | 1.3825 (1.1053–1.7292) | 0.0045 |
| Palliative RT | ||||||||
| No | Reference | |||||||
| Yes | 0.885 (0.814–0.9619) | 0.00406 | 0.8874 (0.8160–0.9652) | 0.00532 | 0.8771 (0.7902–0.9737) | 0.0139 | 0.8563 (0.7711–0.9509) | 0.0037 |
| Tumor size | ||||||||
| ≤5 cm | Reference | Reference | Reference | Reference | ||||
| >5 cm | 1.094 (0.9942–1.218) | 0.0981 | 1.1147 (1.0008–1.2415) | 0.0482 | 0.9059 (0.774–1.060) | 0.2185 | 0.8996 (0.7676–1.0544) | 0.1915 |
| Unknown | 1.307 (1.1859–1.441) | <0.001 | 1.3329 (1.2085–1.4701) | <0.001 | 1.1814 (1.032–1.352) | 0.0153 | 1.2078 (1.0531–1.3852) | 0.0069 |
Abbreviation: RT, radiotherapy.