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. Author manuscript; available in PMC: 2018 Jun 18.
Published in final edited form as: J Bone Miner Res. 2017 Nov 17;33(3):499–509. doi: 10.1002/jbmr.3327

Fig. 3.

Fig. 3

Hyp osteocytes have increased expression markers of perilacunar and canalicular remodeling. (A) RNA was isolated from osteocyte enriched WT and Hyp femoral cortices and subjected to RT-qPCR to quantitate mRNA expression of FGF23, MEPE, and DMP1. (B) mRNA expression of genes implicated in osteocyte perilacunar/canalicular remodeling. (C) Immunohistochemistry for cathepsin K on d14 and d30 tibia and calvaria. (D) Immunohistochemistry for MMP13 on d14 and d30 tibia and calvaria. Data are representative of that obtained from 3 mice per genotype/age. *p < 0.05.