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. 2018 Apr 25;293(24):9210–9222. doi: 10.1074/jbc.RA118.002291

Figure 7.

Figure 7.

Low-complexity regions of Mmi1 are critical for high-affinity binding to DSR RNA. Binding kinetics for YTH-ΔC (A), YTH-ΔN (B), and YTH-ΔNΔC (C) constructs were determined using SwitchSENSE. Association (left panel) and dissociation (right panel) binding curves are shown, as dynamic response (DRup) versus time. Dynamic response is the integrated fluorescence intensity between 2 and 6 μs. Raw data are in gray, and fitted curves are in color or black.