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Peptide-selective effects on agonist affinity, cAMP accumulation, [Ca2+]i mobilization, and pERK. Mutated amino acids with similar effects across peptides are not highlighted. Maps for affinity, cAMP, and pERK include all three peptides. The map for [Ca2+]i includes only GLP-1 and exendin-4. The exendin-P5 peptide is displayed in magenta.
