Table 3. Adjusted means for each of the 8 dimensions of health-related quality of life by baseline categories of adherence to a traditional Mediterranean diet.
The PREDIMED-Plus trial.
| Physical Role | |||||
|---|---|---|---|---|---|
| Adherence to tde traditional Mediterranean diet | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| N | 1567 | 1730 | 1647 | 1486 | |
| Age & sex adjusted | 73.84 (72.08 to 75.60) | 75.75 (74.13 to 77.37) | 77.25 (75.59 to 78.91) | 77.63 (75.84 to 79.42) | <0.001 |
| Multivariable adjusted 1* | 74.49 (72.73 to 76.26) | 76.17 (74.56 to 77.78) | 77.08 (75.43 to 78.73) | 76.64 (74.84 to 78.43) | 0.064 |
| Multivariable adjusted 2** | 74.39 (72.66 to 76.14) | 76.15 (74.56 to 77.74) | 77.07 (75.44 to 78.70) | 76.78 (75.01 to 78.56) | 0.043 |
| Bodily Pain | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| Age & sex adjusted | 60.82 (59.53 to 62.14) | 61.42 (60.22 to 62.61) | 62.56 (61.33 to 63.78) | 64.16 (62.85 to 65.49) | <0.001 |
| Multivariable adjusted 1* | 61.26 (59.96 to 62.55) | 61.75 (60.56 to 62.93) | 62.47 (61.25 to 63.68) | 63.44 (62.11 to 64.75) | 0.011 |
| Multivariable adjusted 2** | 61.15 (59.87 to 62.43) | 61.74 (60.57 to 62.90) | 62.49 (61.29 to 63.68) | 63.53 (62.23 to 64.83) | 0.006 |
| General Health | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| Age & sex adjusted | 60.70 (59.76 to 61.64) | 61.77 (60.91 to 62.63) | 62.85 (61.97 to 63.73) | 64.03 (63.08 to 64.98) | <0.001 |
| Multivariable adjusted 1* | 61.28 (60.36 to 62.22) | 62.10 (61.25 to 62.94) | 62.68 (61.81 to 63.55) | 63.21 (62.27 to 64.16) | 0.002 |
| Multivariable adjusted 2** | 60.93 (60.03 to 61.84) | 62.10 (61.27 to 62.92) | 62.82 (61.98 to 63.68) | 63.42 (62.50 to 64.34) | <0.001 |
| Physical function | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| Age & sex adjusted | 74.54 (73.61 to 75.47) | 75.15 (74.30 to 76.01) | 76.53 (75.65 to 77.41) | 78.53 (77.58 to 79.47) | <0.001 |
| Multivariable adjusted 1* | 75.20 (74.30 to 76.10) | 75.59 (74.77 to 76.41) | 76.39 (75.55 to 77.24) | 77.47 (76.56 to 78.39) | <0.001 |
| Multivariable adjusted 2** | 75.16 (74.27 to 76.04) | 75.59 (74.78 to 76.40) | 76.39 (75.56 to 77.21) | 77.53 (76.63 to 78.43) | <0.01 |
| Vitality | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| Age & sex adjusted | 61.05 (60.00 to 62.10) | 62.88 (61.92 to 63.45) | 64.17 (63.18 to 65.16) | 66.09 (65.03 to 67.16) | <0.001 |
| Multivariable adjusted 1* | 61.80 (60.77 to 62.83) | 63.27 (62.33 to 64.21) | 63.94 (62.97 to 64.91) | 65.10 (64.05 to 66.15) | <0.001 |
| Multivariable adjusted 2** | 61.59 (60.58 to 62.59) | 63.28 (62.36 to 64.20) | 64.00 (63.05 to 64.93) | 65.26 (64.23 to 66.28) | <0.001 |
| Social function | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| Age & sex adjusted | 84.21 (83.17 to 85.26) | 85.58 (84.62 to 86.54) | 86.37 (85.39 to 87.36) | 87.53 (85.39 to 87.36) | <0.001 |
| Multivariable adjusted 1* | 84.69 (83.65 to 85.73) | 85.82 (84.86 to 86.77) | 86.21 (85.23 to 87.19) | 86.93 (85.83 to 88.99) | 0.005 |
| Multivariable adjusted 2** | 84.54 (83.52 to 85.56) | 85.82 (84.90 to 86.76) | 86.21 (85.26 to 87.17) | 87.08 (86.05 to 88.12) | 0.001 |
| Emotional role | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| Age & sex adjusted | 84.09 (82.55 to 85.62) | 86.64 (85.23 to 88.05) | 88.04 (86.59 to 89.49) | 88.26 (86.07 to 89.82) | <0.001 |
| Multivariable adjusted 1* | 84.53 (82.99 to 86.06) | 86.85 (85.44 to 88.25) | 87.87 (86.43 to 89.31) | 87.75 (86.18 to 89.32) | <0.001 |
| Multivariable adjusted 2** | 84.36 (82.85 to 85.87) | 86.88 (85.50 to 88.25) | 87.84 (86.42 to 89.25) | 87.92 (86.39 to 89.45) | <0.001 |
| Mental Health | |||||
| <7 | 7–9 | 9–10 | 11–17 | P for trend | |
| Age & sex adjusted | 72.37 (71.42 to 73.32) | 73.89 (73.03 to 74.77) | 75.13 (74.24 to 76.03) | 76.28 (75.32 to 77.24) | <0.001 |
| Multivariable adjusted 1* | 72.88 (71.94 to 73.82) | 74.13 (73.27 to 74.99) | 74.95 (74.07 to 75.83) | 75.67 (74.71 to 76.53) | <0.001 |
| Multivariable adjusted 2** | 72.69 (71.78 to 73.61) | 74.14 (73.31 to 74.97) | 74.99 (74.13 to 75.84) | 75.81 (74.89 to 76.74) | <0.001 |
*Additionally adjusted for body mass index (kg/m2), physical activity (METs-min/week), smoking status (never, former, current), civil status (single, married, divorced, widowed), educational level (primary school or less, secondary, college or higher)
**Additionally adjusted for high blood pressure, diabetes (dichotomous),depression, chronic obstructive lung disease, and cancer prevalence.