Fig 1. Secondary structure of wild type and recombinant 5S rRNAs.

(a) Human 5S rRNA secondary structure, modified from [26]. (b) 2D structure of rec.5S rRNA versions, mfold predictions corrected manually. Sequences of the anti-replicative insertions (shown in red) correspond to boundaries of the KSS deletion in mtDNA; arrows indicate the deletion point.