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. 2018 Jun 4;14(6):e1007114. doi: 10.1371/journal.ppat.1007114

Fig 8. BLRF2’s partial dependence on DNA replication requires vPIC.

Fig 8

A) Western blot showing levels of the BLRF2 product VCAp23 in EBV ΔBALF2/ΔBcRF1 HEK293 cells. Cells were either uninduced (U), induced by transfection of Rta and Zta expression plasmids (I), induced by transfection of Rta and Zta expression plasmids and trans-complemented by transfection of either only BALF2 (I + BALF2) or both BALF2 and the essential vPIC component BcRF1 (I + BALF2 + BcRF1). B) CAGE-seq tracks corresponding to BLRF2 TSS levels. Treatment conditions are described in Fig 2. Scale marker in the WT track indicates track heights depicted in all tracks for the same TSS cluster. * indicates TSS signal surpassing the indicated scale. Full tracks are available to view in an interactive viewer (https://go.wisc.edu/58sxkb).