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. Author manuscript; available in PMC: 2018 Jun 18.
Published in final edited form as: AAPS J. 2016 Oct 24;19(1):141–149. doi: 10.1208/s12248-016-9999-6

Fig. 6.

Fig. 6

UBM decreased inflammatory markers in human primary chondrocytes a Gene expression data from in vitro human chondrocytes exposed to 10 ng/mL of IL-1β and 1 ng/mL–1 μg/mL of UBM (n = 3). *p < 0.05, **p < 0.01. b Confocal imaging of 1 μg/mL UBM (left) and 100 μg/mL UBM (right) 24 h after addition into cell culture medium. Red = cell membrane (seen at 50% transparency), blue = nucleus, green = UBM. UBM particles appear to be almost entirely encapsulated by the cell membrane after only 24 h