The effect of IWR1 on β-catenin and proBDNF/mBDNF in BV2 cells. BV2 cells were incubated with IWR1(0.1, 1, 10 μM for 0, 1, 3, and 6 h. a β-catenin, proBDNF, and mBDNF were detected by western blotting. b, c, d Quantification of the β-catenin, proBDNF, and mBDNF. (*p < 0.05 vs control (0 h), **p < 0.01 vs control (0 h), ***p < 0.001 vs control (0 h). n = 6, one-way ANOVA)