Table 4.

Studies relating to cross-reactivity between the anti-HLA immune response and pig antigens to investigate whether HLA sensitization is detrimental to pig xenotransplantation

HLA sensitization is detrimental
Author/Year	REF.
Naziruddin et al, 1998	30
Taylor et al, 1998	31
Barreau et al, 2000	35
Popma et al, 2000	36
Mulder et al, 2000	37
Oostingh et al, 2002	38
Varela et al, 2003	39
Mulder et al, 2010	42
Martens et al, 2017	32

HLA sensitization is not detrimental
Author/Year	REF.
Bartholomew et al, 1997	34
Wong et al, 2006	40
Hara et al, 2006	41
Zhang et al	29