Table 3.
Sedative Use and Neurocognitive outcomes
| Outcome | Facemask NIV (n=39) | Helmet NIV (n=44) | p-value | ||
|---|---|---|---|---|---|
|
| |||||
| No. ICU days spent in: | 286 ICU days | 215 ICU days | |||
| Delirium | 82/286 | 28.7% | 34/215 | 15.8% | 0.0007 |
| Coma | 40/286 | 14.0% | 31/215 | 14.2% | 0.89 |
| CAM-ICU Normal | 164/286 | 57.3% | 150/215 | 62.7% | 0.004 |
| No. Hospital days spent in: | 414 Hospital days | 446 Hospital days | |||
| Delirium | 132/414 | 31.9% | 70/446 | 15.7% | 0.00001 |
| Coma | 39/414 | 9.4% | 34/446 | 7.6% | 0.34 |
| CAM-ICU Normal | 243/414 | 58.7% | 342/446 | 76.7% | 0.00001 |
| Sedative Details | |||||
| No. receiving dexmedetomidine | 13 | 33.3% | 17 | 38.6% | 0.62 |
| No. receiving propofol | 16 | 41% | 7 | 15.9% | 0.01 |
| No. receiving midazolam | 16 | 41% | 15 | 34% | 0.52 |
| No. receiving IV opiate | 27 | 69% | 23 | 52.3% | 0.12 |
Data are expressed in n (%), where appropriate
ICU= Intensive Care Unit; CAM= Confusion Assessment Method