Table 1.
Primary and Secondary Endpoints
Primary Endpoint | 1. Composite of cardiovascular death, nonfatal myocardial infarction, hospitalization for unstable angina, hospitalization for heart failure, or resuscitated cardiac arrest. |
Major Secondary Endpoints | 1. Composite of cardiovascular death or nonfatal myocardial infarction 2. Angina per SAQ Angina Frequency Scale |
Other Secondary Endpoints | 1. Composite of cardiovascular death, nonfatal myocardial infarction, or stroke 2. Composite of cardiovascular death, nonfatal myocardial infarction, hospitalization for unstable angina, hospitalization for heart failure, resuscitated cardiac arrest, or stroke 3. Individual components of the primary endpoint 4. All-cause death 5. Stroke 6. Composite endpoints incorporating all cause death 7. Composite endpoints incorporating other definitions of MI1 8. Disease-specific quality of life per SAQ Quality of Life Scale 9. Health resource utilization, costs, and cost-effectiveness |
See Table S5 for definitions of clinical endpoints.
SAQ = Seattle Angina Questionnaire