Figure 2.

Sequence comparison of J3-crystallin with human, chicken, and zebrafish prosaposin. Prosaposin amino acids that are identical to those of J3-crystallin in the alignment are highlighted in black; prosaposin residues that are similar to those in J3-crystallin are highlighted in gray. The six characteristic cysteines identifying the two putative saposin motifs in J3-crystallin are indicated under the J3-crystallin sequence. The accession numbers of the human, chicken, and zebrafish prosaposins are given in Methods.