Table S1. Tumor cells percentage and DNA/RNA amount extracted from the thoracic biopsy specimens and pleural effusion specimen.

Sample ID	Thoracic biopsy specimen				Pleural effusion specimen
	Tumor cell %	DNA amount (ng)	RNA amount (ng)		Tumor cell %	DNA amount (ng)	RNA amount (ng)
#1	25	378	825		11–15	540	980
#2	20	240	600		1–5	56	116
#3	20	160	465		6–10	65	145
#4	30	460	960		11–15	78	136
#5	25	420	1,110		15–20	1,510	2,978
#6	25	200	540		6–10	75	132
#7	25	330	712		1–5	81	178
#8	20	290	645		6–10	68	149
#9	50	630	1,222		1–5	53	140
#10	45	540	1,177		1–5	98	194
#11	35	380	900		6–10	228	479
#12	30	250	585		11–15	1,830	3,240
#13	20	230	525		16–20	1,000	1,680
#14	30	420	945		6–10	160	397
#15	25	350	750		16–20	720	1,875
#16	25	270	510		11–15	635	1,770
#17	40	460	930		16–20	144	254
#18	30	340	705		16–20	164	259
#19	35	490	1,005		6–10	2,960	4,730
#20	40	560	1,260		16–20	725	1,828
#21	35	390	795		1–5	360	950
#22	30	270	615		6–10	60	240
#23	40	460	1,035		11–15	194	350
#24	35	420	795		1–5	165	430
#25	25	380	780		16–20	740	1,380
#26	35	420	945		1–5	143	320
#27	30	360	885		6–10	115	278
#28	20	220	510		6–10	62	153
#29	25	330	750		16–20	1,000	2,312
#30	40	530	1,140		6–10	248	560