Fig. 2.

NEET proteins’ structures solved by X-ray crystallography. Structure of monomeric bacterial MiNT (blue colored; PDB-ID: 3tbn [14]), and dimeric (monomers A are reported with lighter colors) At-NEET (green, 3s2q [30]), mitoNEET (red, 2qh7 [15]) and NAF-1 (brown, 4oo7 [38]) proteins, and their superposition. The [2Fe-2S] cluster atoms are shown in orange-yellow spheres. The superposition of the four proteins shows the high structural similarity shared between the NEET proteins. The crystallized part of the homodimeric NEET proteins is limited to the cytosolic domain (fully colored part in Fig. 1) without the linkers to the membrane and the intra-organelle parts