Table 1.
Summary of demographic characteristics and plasma measures
| Control (n = 104) | SSD (n = 106) | Test-statistic | p-value | |
|---|---|---|---|---|
| Age (years) | 35.4 ± 14.3 | 36.3 ± 13.4 | t = 0.47 | .64 |
| Smoker/non-smoker | 26/78 | 37/69 | χ2 = 2.45 | .12 |
| Male/female | 59/45 | 69/37 | χ2 = 1.54 | .21 |
| Duration of illness (years) | n/a | 14.1 ± 12.6 | n/a | |
| Body mass index | 26.8 ± 5.3 | 27.9 ± 6.2 | t = 1.39 | .17 |
| Kynurenine (pmol/μl) | 1.16 ± 0.39 | 1.07 ± 0.42 | t = 1.55 | .12 |
| Kynurenic acid (fmol/μl) | 31.8 ± 14.0 | 26.3 ± 12.8 | t = 2.94 | .004 |
| IL-6 (pg/ml) | 4.08 ± 9.5 | 9.11 ± 23.8 | Z = 2.52 | .012 |
| IL-10 (pg/ml) | 2.37 ± 6.7 | 4.16 ± 10.2 | Z = 2.53 | .012 |
| TNF-α (pg/ml) | 7.74 ± 17.0 | 15.27 ± 34.9 | Z = 1.34 | .18 |
| IFN-γ (pg/ml) | 0.44 ± 1.56 | 0.36 ± 0.73 | Z = 0.92 | .34 |
Variance reported as ± standard deviation. Values were mean ± standard deviation
SSDschizophrenia spectrum disorder