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. 2018 May 2;16(1):19–26. doi: 10.3892/ol.2018.8613

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Genes, proteins or miRNAs associated with MALAT1. The upstream regulators during the transcriptional and posttranscriptional procession and the downstream genes modulated by MALAT1 are exhibited. In addition, reciprocal interaction and other associations between MALAT1 and other genes, proteins or miRNAs are shown. MALAT1, metastasis-associated lung adenocarcinoma transcript 1; SOX17, sex-determining region-Y-box 17; SRSF1, serine/arginine-rich splicing factor 1; YAP, yes-associated protein 1; Bcl-2, B-cell lymphoma-2; miR/miRNA, microRNA; ABCA1, ATP-binding cassette transporter member 1; ROBO1, roundabout guidance receptor 1; GPC6, glupican 6; CDCP1, CUB domain-containing protein 1; LPHN2, latrophilin-2, a cell-adhesion G protein-coupled receptor and presumptive α-latrotoxin receptor; MIA2, melanoma inhibitory activity 2; LTBP3, latent transforming growth factor β-binding protein 3; PTBP2, polypyrimidine tract binding protein 2; SFPQ, splicing factor proline-glutamine rich; suz12, suz12 polycomb repressive complex 2 subunit; Ezh2, enhancer of zeste homolog 2; Bax, Bcl-2-associated X protein; Bcl-xl, B-cell lymphoma-extra-large; TDP43, TAR DNA-binding protein 43; lncRNA, long non-coding RNA; AKAP-9, A-kinase anchor protein-9.