Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 18;9(7):722. doi: 10.1038/s41419-018-0759-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a The level of SNHG7 transfection with siSNHG7 or siControl was analyzed by qRT-PCR. b Growth curves of SW620 and LOVO cells after transfection with siSNHG7 or siControl were determined via CCK-8 assays. c Colony formation assays showed that knockdown of SNHG7 inhibited CRC cell proliferation. d Suppression of SNHG7 expression attenuated the proliferation of CRC cells by EdU assay. Scale bars = 50 μm. e The levels of cleaved PARP, cleaved caspase-7, and cleaved caspase-3 following SNHG7 silenced in CRC cells were determined via western blot. f Flow cytometry assay showed that silencing of SNHG7 increased the rate of apoptosis in CRC cells. g Flow cytometry assay showed that siSNHG7 resulted in S arrest in CRC cells. The cell cycle distribution was exhibited. h siSNHG7 resulted in a slower closing of scratch wound by wound-healing assay. Scale bars = 50 μm. i Transwell invasion assay was measured and the results were expressed as the number of invaded cells per field. Scale bars = 20 μm. The error bars in all graphs represented SD, and each experiment was repeated three times. *p < 0.05