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. 2018 May 7;16(1):105–112. doi: 10.3892/ol.2018.8653

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Copyright: © Xia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Downregulated of CITED1 inhibits migration and invasion in papillary thyroid carcinoma cell lines. (A) Migration assay (magnification, ×10) and (B) Relative quantification of migrating cell number. Migrating cell numbers were lower in the TPC1 and BCPAP cells transfected with siRNA, compared with that in the NC group. (C) Invasion assay (magnification, ×10) and (D) relative quantification of invading cell numbers. The invading cell number was lower in cells transfected with siRNA, compared with that in the NC group. Data are presented as the mean ± standard deviation ranges of expression. ***P<0.001, compared with the NC group using two-way analysis of variance and an LSD post hoc test. CITED1, Cbp/p300-interacting transactivators with glutamic acid [E] and aspartic acid [D]-rich C-terminal domain 1; siRNA, small interfering RNA; NC, normal control.