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. 2018 May 4;16(1):137–144. doi: 10.3892/ol.2018.8638

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Copyright: © Gao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Enhancer dual luciferase reporter assay analysis of functionality. The relative luciferase activity of the candidate promoters in (A) lung cancer cells A549, H460, H446 and (B) the squamous cell carcinoma cell line Eca-109 and normal cell 293T. *P<0.05 vs DKK1. DKK1, dickkopf 1; TRE, transcriptional regulatory element; HS2, DNase I hypersensitive site II.