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. 2018 May 9;16(1):308–316. doi: 10.3892/ol.2018.8676

Table VII.

Distribution and differences in risk ratios between the 7th edition of the UICC/AJCC staging system and the proposed novel N staging system.

Risk ratio (95% CI)

N stage No. Distant metastasis survival OS
Proposed system
N0 64 (13.0) 1 1
N1 161 (32.7) 7.557 (1.009–56.613)a 4.596 (1.077–19.609)a
N2 223 (45.3) 13.827 (1.903–100.486)a 10.000 (2.431–41.132)a
N3 44 (8.9) 30.123 (3.993–227.251)a 18.584 (4.282–80.651)a
UICC/AJCC system
N0 64 (13.0) 1 1
N1 159 (32.3) 6.316 (0.834–47.812) 3.955 (0.917–17.050)
N2 226 (45.9) 13.288 (1.827–96.612)a 9.719 (2.361–40.006)a
N3a 11 (2.2) 51.936 (6.243–432.084)a 36.384 (7.268–182.153)a
N3b 32 (6.5) 38.744 (5.091–294.830)a 23.544 (5.369–103.245)a
a

P<0.05 compared with N0. OS, overall survival; UICC/AJCC, Union for International Cancer Control/American Joint Committee on Cancer; CI, confidence interval.