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. Author manuscript; available in PMC: 2018 Dec 18.
Published in final edited form as: Chem Res Toxicol. 2017 Nov 28;30(12):2218–2228. doi: 10.1021/acs.chemrestox.7b00288

Table 4.

Binding affinity and rate constants measured on OctetRED96 of monoclonal antibody depY for proteins modified on tyrosine by diethoxyphosphate.

Protein kon (1/Ms) koff (1/s) Kd (M) Chi2 R2
Porcine tubulin-OP 2.44 E+05 <1.0 E-7 <1.0 E-12 0.014 0.99
Porcine tubulin control NA NA No binding NA NA
Casein-OP 1.82 E+05 <1.0 E-7 <1.0 E-12 0.004 0.97
Casein control NA NA No binding NA NA
Ovalbumin-YPF-OP 1.40 E+05 <1.0 E-7 <1.0 E-12 0.027 0.96
Ovalbumin-YPF control NA NA No binding NA NA
Bovine albumin-LYGLPR-OP 2.08 E+05 <1.0 E-7 <1.0 E-12 0.176 0.93
Bovine albumin-LYGLPR control NA NA No binding NA NA

Chi2 values less than 1 are highly significant. NA, not applicable.