Table 2.

Analysis of the frequency distributions of the COL5A1 rs12722-rs13946 haplotype in the study group and the control group for the three genetic models - dominant, recessive and additive.

(Haplotype (rs12722-rs13946))	Control (n=211)	Study (n=134)	Dominant model (global-stat = 4.35, p = 0.226)	Recessive model (global-stat = 4.72, p = 0.193)	Additive model (global-stat = 2.75, p = 0.253)
T-T	55%	58%	0.63, p = 0.525	0.82, p = 0.411	0.90, p = 0.366
C-C	31%	26%	-2.06, p = 0.038	0.12, p = 0.901	-1.60, p = 0.107
C-T	14%	1%	0.32, p = 744	1.90, p = 0.057	0.76, p = 0.442

global-stat –association of all haplotypes of the trait; hap.score – measure individual haplotype association to the trait; Significant p-values are in bold (p<0.05).