Table 7.
Top 10 predicted drugs associated with Alzheimer’s disease
| Index | Drug Name | Drug MeSH ID | DrugBank ID | PubChem CID | Score(normalized) | Evidence |
|---|---|---|---|---|---|---|
| 1 | Nitroprusside | D009599 | DB00325 | 11,963,622 | 1 | N.A. |
| 2 | Tamoxifen | D013629 | DB00675 | 2,733,526 | 0.7644 | N.A. |
| 3 | Olanzapine | C076029 | DB00334 | 4585 | 0.7269 | A clinical study [46] |
| 4 | Sucralfate | D013392 | DB00364 | 70,789,197 | 0.7223 | N.A. |
| 5 | Levodopa | D007980 | DB01235 | 6047 | 0.6893 | An animal study [47] |
| 6 | Malondialdehyde | D008315 | DB03057 | 10,964 | 0.6767 | A clinical study [48] |
| 7 | Progesterone | D011374 | DB00396 | 5994 | 0.6695 | An animal study [49] |
| 8 | Valproic Acid | D014635 | DB00313 | 3121 | 0.6625 | An animal study [50] |
| 9 | Scopolamine Hydrobromide | D012601 | DB00747 | 3,000,322 | 0.6522 | N.A. |
| 10 | Ethanol | D000431 | DB00898 | 702 | 0.6402 | A clinical study [51] |
Scores are normalized by using ((score-min)/(max-min))