Table 2.
Transfusion history of the 11 patients, in whom platelet transfusion resulted in 13 newly detectable Rh antibodies
| Patient | Known antibody | New ntibody | Date of detection | Days until detection | First incompatible transfusion | Type of first incompatible transfusion | Last incompatible transfusion before detection | Date of last negative type and screen test | Negative type & screens between first incompatible transfusion and detection | Negative type & screens before first incompatible transfusion | Antigen+/total units |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RBC | BC-PC | AP-PC | ||||||||||||
| 1 | none | anti-f* | 24.08.15 | 3 | 21.08.15 | AP-PC | n.a. | n.a. | n.a. | n.a. | 0/13 | 0 | 1/1 (f-pos) | |
| 2 | none | anti-D* 1 | 08.10.15 | 28 | 10.09.15 | BC-PC | 10.09.15 (BC) | 09.09.15 | 0 | 2 | 0/3 | 1/1 (D-pos) | 0 | |
| 3 | none | anti-c /-E | 10.11.15 | 40 | 01.10.15 | BC-PC | 19.10.15 | 02.11.15 | 7 (c-neg) | 3 (c-neg) | 0/12 | 10/10 (c-pos) | 5/7 (c-pos) | |
| 36 | (c-pos) | (c-pos) | (BC, E+) | 6 (E-neg) | 4 (E-neg) | 7/10 (E-pos) | 1/7 (E-pos) | |||||||
| 05.10.15 | BC-PC | 19.10.15 | ||||||||||||
| (E-pos) | (E-pos) | (BC, c+) | ||||||||||||
| 4 | none | anti-D | 15.12.15 | 109 | 28.08.15 | BC-PC | 28.08.15 (BC) | 01.09.15 | 1 | 2 | 0/8 | 1/1 (D-pos) | 0 | |
| 5 | none | anti-D2 | 22.05.16 | 25 | 27.04.16 | BC-PC | 27.04.16 (BC) | 12.05.16 | 2 | 1 | 0/8 | 1/1 (D-pos) | 0/1 (D-pos) | |
| 6 | anti-K & anti-Co(b) | anti-D* | 03.06.16 | 6 | 28.05.16 | BC-PC | 30.05.16 (BC) | 28.05.16 | 0 | 1 | 0 | 5/6 (D-pos) | 0 | |
| 7 | none | anti-c /-E | 03.06.16 | 1414 | 19.07.12 (c-pos) 19.07.12 (E-pos) |
AP-PC (c-pos) AP-PC (E-pos) |
31.05.16 (c-pos) 31.05.16 (c-pos) |
27.05.16 | 26 | 1 | 0/41 | 24/24 (c-pos) 17/24 (E-pos) |
13/19 (c-pos) 5/19 (E-pos)3 |
|
| 8 | anti-E | anti-D | 23.08.16 | 41 | 13.07.16 | BC-PC | 04.08.16 (BC) | 20.08.16 | 8 | 1 | 0/11 | 2/2 (D-pos) | 1/10 (D-pos) | |
| 9 | none | anti-E | 19.11.16 | 57 | 23.09.16 | BC-PC | 17.11.16 (BC) | 15.11.16 | 12 | 2 | 0/25 | 18/25 (E-pos) | 6/21 (E-pos) | |
| 10 | none | anti-D | 03.08.17 | 46 | 18.06.17 | AP-PC | 02.08.17 (BC) | 30.07.17 | 18 | 5 | 0/24 | 8/8 (D-pos) | 5/9 (D-pos) | |
| 11 | anti-K & anti-Kp(a) | anti-E* | 02.09.17 | 13 | 20.08.17 | BC-PC | 28.08.17 (BC) | 25.08.17 | 1 | 3 | 0/7 | 5/5 (E-pos) | 0/4 (E-pos) | |
n.a = Data not available/applicable.
*
Probably booster-effect of previously immunized patient.
1
Day 28 post transfusion, but 4+ reactivity.
2
Day 25 post transfusion, but weak reactivity.
3
Rh phenotype from one donor is missing.