Table 13.
GO terms (biological processes) found for the 59 genes with a high number of human-unique intron motifs
| GO term | GO term id | No. genes | FDR |
|---|---|---|---|
| System development | GO:0048731 | 37 | 1.39E-08 |
| Multicellular organism development | GO:0007275 | 38 | 7.48E-08 |
| Anatomical structure development | GO:0048856 | 39 | 9.04E-08 |
| Developmental process | GO:0032502 | 40 | 1.06E-07 |
| Multicellular organismal process | GO:0032501 | 43 | 3.78E-07 |
| Nervous system development | GO:0007399 | 25 | 7.65E-07 |
| Cell-cell adhesion via plasma-membrane adhesion molecules | GO:0098742 | 9 | 3.47E-05 |
| Cell-cell adhesion | GO:0098609 | 11 | 8.49E-05 |
| Animal organ development | GO:0048513 | 25 | 2.47E-04 |
| Neuron differentiation | GO:0030182 | 14 | 3.44E-04 |
| Homophilic cell adhesion via plasma membrane adhesion molecules | GO:0007156 | 7 | 5.16E-04 |
| Biological adhesion | GO:0022610 | 13 | 9.89E-04 |
| Cell adhesion | GO:0007155 | 13 | 1.01E-03 |
| Cellular developmental process | GO:0048869 | 26 | 1.19E-03 |
| Neurogenesis | GO:0022008 | 16 | 2.13E-03 |
| Cell differentiation | GO:0030154 | 25 | 2.70E-03 |
| Generation of neurons | GO:0048699 | 15 | 4.06E-03 |
| Anatomical structure morphogenesis | GO:0009653 | 18 | 5.49E-03 |
| Neuron development | GO:0048666 | 11 | 5.75E-03 |
| Neuromuscular process | GO:0050905 | 5 | 1.04E-02 |
| Sensory organ development | GO:0007423 | 9 | 1.10E-02 |
| Neuromuscular process controlling balance | GO:0050885 | 4 | 1.37E-02 |
| Vocalization behavior | GO:0071625 | 3 | 2.08E-02 |
| Cell projection morphogenesis | GO:0048858 | 8 | 2.63E-02 |
| Neuron projection development | GO:0031175 | 9 | 2.64E-02 |
| Cell development | GO:0048468 | 14 | 2.70E-02 |
| Retina layer formation | GO:0010842 | 3 | 2.73E-02 |
| Neuron projection morphogenesis | GO:0048812 | 8 | 2.76E-02 |
| Plasma membrane bounded cell projection morphogenesis | GO:0120039 | 8 | 2.81E-02 |
| Axonogenesis | GO:0007409 | 7 | 3.04E-02 |
| Cell part morphogenesis | GO:0032990 | 8 | 3.22E-02 |
| Cell morphogenesis | GO:0000902 | 9 | 3.59E-02 |
| Axon development | GO:0061564 | 7 | 4.66E-02 |
Statistically significant human-specific motif lists (lengths 6–10) were determined for introns. These motifs were searched for in the human intron sequence set. The top 100 genes with the highest number of such motifs in their introns were listed. Those 59 genes were listed which belonged to at least 3 top 100 lists, and plugged into the Gene Ontology database. Below are listed 33 GO terms associated with these 59 genes