Table 3.
Healthy Controls (HC) | PD ON | PD OFF | Effect Size & p-value | ||||
---|---|---|---|---|---|---|---|
HC vs PD ON | HC vs PD OFF | ON vs OFF | |||||
SPARC | Acc | -5.17 ± 0.79 | −6.11 ± 0.74 | −6.74 ± 0.64 | 1.25 (< 0.001) | 2.29 (0.001) | < 0.001 |
V | − 5.08 ± 0.74 | − 5.22 ± 0.78 | − 5.74 ± 0.88 | 0.17 (0.107) | 0.78 (0.001) | < 0.001 | |
AP | −5.57 ± 0.74 | −5.80 ± 0.80 | − 6.44 ± 0.77 | 0.30 (0.190) | 1.14 (0.001) | < 0.001 | |
ML | − 5.44 ± 0.32 | −5.60 ± 0.48 | −5.96 ± 0.50 | 0.35 (0.388) | 1.13 (0.005) | < 0.001 | |
Gyr | −4.87 ± 0.55 | −5.00 ± 0.52 | −5.43 ± 0.53 | 0.25 (0.156) | 1.06 (< 0.001) | < 0.001 | |
Yaw | −5.96 ± 0.81 | −5.92 ± 0.85 | −6.47 ± 0.82 | − 0.05 (0.037) | 0.63 (0.002) | < 0.001 | |
Roll | − 5.80 ± 0.73 | −5.97 ± 0.60 | −6.51 ± 0.70 | 0.26 (0.229) | 1.01 (0.007) | < 0.001 | |
Pitch | −6.28 ± 0.75 | −6.55 ± 0.86 | − 7.09 ± 0.91 | 0.32 (0.365) | 0.94 (0.002) | < 0.001 | |
Harmonic ratios | V | 3.10 ± 0.90 | 2.75 ± 0.82 | 2.95 ± 0.85 | 0.42 (0.998) | 0.17 (0.092) | < 0.001 |
AP | 2.08 ± 0.48 | 2.04 ± 0.74 | 2.54 ± 0.93 | 0.06 (0.800) | − 0.55 (0.240) | < 0.001 | |
ML | 0.60 ± 0.11 | 0.56 ± 0.09 | 0.52 ± 0.08 | 0.33 (0.002) | 0.89 (< 0.001) | < 0.001 | |
Mean Gait Speed | – | 1.18 ± 0.24 | 1.16 ± 0.20 | 1.13 ± 0.19 | 0.05 (0.028) | 0.21 (0.008) | 0.117 |
Stride Time | Mean | 1.04 ± 0.06 | 1.09 ± 0.09 | 1.09 ± 0.09 | − 0.62 (0.048) | − 0.53 (0.365) | 0.550 |
Variability | 3.43 ± 1.17 | 4.72 ± 3.05 | 5.84 ± 4.92 | − 0.48 (0.044) | − 0.57 (0.055) | 0.826 |
Note: Significant results are displayed in bold
Analysis was also performed without controlling for weight which did not modify the outcomes