Table 4.
Healthy Controls (HC) | PD ON | PD OFF | Effect Size & p-value | ||||
---|---|---|---|---|---|---|---|
HC vs PD ON | HC vs PD OFF | ON vs OFF | |||||
SPARC | Acc | −5.08 ± 0.71 | −6.37 ± 0.64 | −6.88 ± 0.64 | 1.95 (< 0.001) | 2.69 (0.001) | 0.003 |
V | −4.25 ± 0.14 | − 4.85 ± 0.61 | − 5.77 ± 0.76 | 1.36 (< 0.001) | 2.78 (0.001) | < 0.001 | |
AP | −5.42 ± 0.70 | −5.83 ± 0.42 | − 6.69 ± 0.47 | 0.73 (0.033) | 2.18 (< 0.001) | < 0.001 | |
ML | −5.69 ± 0.56 | −5.33 ± 0.43 | −5.38 ± 0.49 | − 0.73 (0.025) | − 0.61 (0.060) | 0.934 | |
Gyr | − 5.01 ± 0.64 | −5.30 ± 0.56 | −5.83 ± 0.71 | 0.49 (0.120) | 1.23 (< 0.001) | 0.009 | |
Yaw | −5.93 ± 0.82 | − 6.14 ± 0.84 | − 6.76 ± 0.86 | 0.26 (0.408) | 1.00 (0.002) | 0.030 | |
Roll | − 5.91 ± 0.90 | − 6.25 ± 0.75 | −6.75 ± 0.68 | 0.41 (0.190) | 1.06 (0.002) | 0.013 | |
Pitch | −6.30 ± 0.85 | −6.77 ± 0.88 | −7.61 ± 1.10 | 0.54 (0.087) | 1.33 (< 0.001) | 0.005 | |
Harmonic ratios | V | 2.62 ± 0.65 | 2.53 ± 0.60 | 2.99 ± 0.78 | 0.14 (0.648) | − 0.52 (0.104) | 0.010 |
AP | 1.02 ± 0.46 | 1.14 ± 0.55 | 1.98 ± 0.53 | − 0.25 (0.424) | − 0.52 (< 0.001) | < 0.001 | |
ML | 0.63 ± 0.12 | 0.57 ± 0.09 | 0.52 ± 0.06 | 0.52 (0.100) | 1.18 (0.001) | 0.112 | |
Mean Gait Speed | – | 1.20 ± 0.23 | 1.10 ± 0.20 | 1.04 ± 0.23 | 0.48 (0.127) | 0.72 (0.026) | 0.509 |
Stride Time | Mean | 1.05 ± 0.04 | 1.12 ± 0.10 | 1.09 ± 0.12 | − 0.87 (0.004) | − 0.43 (0.143) | 0.536 |
Variability | 3.50 ± 1.27 | 3.67 ± 1.56 | 5.82 ± 5.05 | − 0.12 (0.717) | − 0.066 (0.054) | 0.550 |
Note: Significant results are displayed in bold