Fig. 4.

Charge characteristic and functional subdivision of the cytoskeletal protein families. a The charged amino acid contents of Actins, tubulins and intermediate filaments. To transform charged AA contents for each cytoskeletal protein, which were divided by the eukaryotes average acid (0.114955653) or basic AA (0.142665842) content. Effectively, this transformed the data and showed the difference between these proteins and eukaryotic proteins as a whole. Pink color (value > 1) shows the content higher than the mean content of the eukaryotes, blue color (value < 1) shows the content lower than the mean content of the eukaryotes. b Functional classification for all cytoskeletal proteins, by analysis their relationship with their associated upstream and downstream proteins. c Functional classification for Lamin, InterIV, TnC and TPM