Table 1.
Participant characteristics.
| HCS (N = 34) |
PSZ (N = 48) |
Statistic | P value | |
|---|---|---|---|---|
| Age | 38.53 (11.44) | 38.38 (9.58) | t = 0.07 | 0.95 |
| Gender (M | F) | 19 | 15 | 30 | 18 | φ = 0.36 | 0.55 |
| Race (African American | Caucasian | Other) | 14 | 18 | 2 | 16 | 28 | 4 | φ = 0.60 | 0.74 |
| Participant education | 14.88 (2.06) | 13.21 (2.44) | t = 3.27 | 0.002 |
| Maternal education | 14.21 (2.56) | 14.21 (2.84) | t = −0.004 | 0.99 |
| Paternal education | 15.03 (3.92) | 14.82 (3.59) | t = 0.87 | 0.39 |
| Neurocognitive test results | ||||
| WASI-II IQ | 109.44 (11.23) | 92.54 (28.7) | t = 3.25 | <0.001 |
| WRAT 4 | 108.65 (14.1) | 93.54 (29.74) | t = 2.74 | 0.01 |
| WTAR | 110.68 (13.45) | 94.17 (30.73) | t = 2.93 | <0.001 |
| MD processing speed | 52.09 (11.66) | 42.76 (11.41) | t = 3.58 | <0.001 |
| md attention vigilance | 50.68 (10.54) | 42.26 (12.18) | t = 3.23 | <0.001 |
| MD working memory | 50.71 (10.61) | 41.85 (11.18) | t = 3.58 | <0.001 |
| MD verbal learning | 49.35 (8.41) | 38.5 (8.28) | t = 5.76 | <0.001 |
| MD visual learning | 44.97 (11.02) | 38.85 (10.39) | t = 2.54 | 0.01 |
| MD reasoning | 50.91 (9.93) | 44.02 (10.02) | t = 3.05 | <0.001 |
| MD social cognition | 55.26 (6.59) | 42.74 (11.16) | t = 5.83 | <0.001 |
| MCT overall | 50.5 (9.92) | 36.11 (12.18) | t = 5.64 | <0.001 |
| Antipsychotic medication | ||||
| Total CPZ | 510.76 (290.21) | |||
| Total haloperidol | 10.73 (6.53) | |||
| Clinical ratings | ||||
| BPRS positive | 2.05 (1.16) | |||
| BPRS negative | 1.87 (0.61) | |||
| BPRS disorganization | 1.25 (0.32) | |||
| BPRS total | 33.39 (11.26) | |||
| SANS AA | 21.03 (8.55) | |||
| SANS EE | 13.7 (8.62) | |||
| SANS total | 27.15 (10.94) | |||
WASI = Wechsler Abbreviated Scale of Intelligence; WRAT = Wide Range Achievement Test; WTAR = Wechsler Test of Adult Reading; MD = MCCB (MATRICS Consensus Cognitive Battery) Cognitive Domain; MCT = MCCB Composite Total; CPZ = Chlorpromazine equivalent; BPRS=Brief Psychiatric Rating Scale; SANS=Scale for the Assessment of Negative Symptoms; AA = Apathy-Avolition; EE = Emotional Expressivity.