Table I.
Characteristics of the included studies.
| Author (refs.) | Year of publication | Country | n | Number of women, n (%) | Dropout, n (%) | Mean age, years | Intervention dose, mg tid | Comparators | Duration | Obesity, % | Diagnosis | Study type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chen et al (12) | 2006 | China | 30 | 5 (16.7) | 0 (0) | 37.8 | 120 | No control | 24 weeks | 100.0 | NAFLD | Single-arm trial |
| Fan et al (22) | 2004 | China | 60 | 23 (38.3) | 2 (3.3) | 36.5 | 120 | No control | 24 weeks | 100.0 | NAFLD | Single-arm trial |
| Harrison et al (13) | 2004 | USA | 10 | 6 (60.0) | 0 (0) | 54.4 | 120 | No control | 6 months | 100.0 | NASH | Single-arm trial |
| Harrison et al (23) | 2009 | USA | 50 | 0 (0) | 9 (18.0) | 47 | 120 | Vitamin E (800 IU) + 1,400-calorie diet | 36 weeks | 100.0 | NASH | RCT |
| Hussein et al (24) | 2007 | Israel | 16 | 10 (62.5) | 2 (12.5) | 42 | 120 | No control | 6 months | 100.0 | NASH | Single-arm trial |
| Ali Khan et al (11) | 2017 | India | 112 | 35 (31.3) | 14 (12.5) | 58.5 | 120 | Diet | 16 weeks | 100.0 | NAFLD | RCT |
| Zelber-Sagi et al (17) | 2006 | Israel | 52 | 25 (48.1) | 8 (15.4) | 47.7 | 120 | Placebo | 6 months | 71.2 | NAFLD | RCT |
NAFLD, non-alcoholic fatty liver; NASH, non-alcoholic steatohepatitis; RCT, randomized controlled trial; tid, three times a day.