Table I.
Top 30 most significantly up- and downregulated differentially expressed genes.
| A, Upregulated genes | ||||
|---|---|---|---|---|
| Gene probe ID | Gene symbol | Description | P-value | Log fold change |
| 154240685 | FGD6 | FYVE, RhoGEF and PH domain-containing 6 | 9.58E-09 | 3.86 |
| 349501059 | CHEK1 | Checkpoint kinase 1 | 3.22E-07 | 4.34 |
| 61743966 | CTBP1 | C-terminal-binding protein 1 | 3.29E-07 | 3.63 |
| 168229167 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 6.76E-07 | 5.38 |
| 154800452 | TROAP | Trophinin-associated protein | 7.45E-07 | 5.41 |
| 157419137 | LAMC2 | Laminin subunit gamma 2 | 1.57E-06 | 4.8 |
| 19882252 | CST2 | Cystatin-SA | 1.77E-06 | 4.71 |
| 748821156 | CKAP2L | Cytoskeleton-associated protein 2-like | 2.44E-06 | 3.93 |
| 300794717 | WDHD1 | WD repeat and HMG-box DNA-binding protein 1 | 4.42E-06 | 4.05 |
| 938148819 | MMP11 | Matrix metallopeptidase 11 | 1.23E-05 | 6.10 |
| 444189305 | FAM83B | Family with sequence similarity 83 member B | 3.77E-05 | 5.82 |
| 54607054 | GJB3 | Gap junction protein beta 3 | 1.36E-04 | 4.90 |
| 148806907 | FNDC1 | Fibronectin type III-domain containing 1 | 1.45E-04 | 4.41 |
| 379056370 | CDCA8 | Cell division cycle-associated 8 | 1.66E-04 | 4.01 |
| 748983174 | CNBD2 | Cyclic nucleotide-binding domain-containing 2 | 2.68E-04 | 6.61 |
| B, Downregulated genes | ||||
| Gene probe ID | Gene symbol | Description | P-value | Log fold change |
| 118498349 | CTRB2 | Chymotrypsinogen B2 | 8.80E-34 | −10.15 |
| 236459772 | CELA2A | Chymotrypsin-like elastase family member 2A | 3.21E-29 | −9.71 |
| 54607079 | CPB1 | Carboxypeptidase B1 | 9.23E-29 | −10.98 |
| 38016927 | PLA2G1B | Phospholipase A2 group IB | 8.53E-25 | −10.78 |
| 747165370 | CPA1 | Carboxypeptidase A1 | 1.09E-21 | −11.95 |
| 58331210 | CELA2B | Chymotrypsin-like elastase family member 2B | 3.17E-20 | −8.90 |
| 440309868 | CEL | Carboxyl ester lipase | 5.85E-18 | −9.68 |
| 734703929 | PNLIPRP1 | Pancreatic lipase-related protein 1 | 1.14E-14 | −8.37 |
| 236460049 | CELA3A | Chymotrypsin-like elastase family member 3A | 2.42E-14 | −10.80 |
| 357588512 | CLPS | Colipase | 1.88E-12 | −12.09 |
| 310923201 | PRSS1 | Protease, serine 1 | 2.48E-10 | −11.52 |
| 217416389 | CPA2 | Carboxypeptidase A2 | 3.24E-10 | −11.27 |
| 62526042 | CTRC | Chymotrypsin 2 | 7.93E-09 | −10.82 |
| 1010226556 | CELA3B | Chymotrypsin-like elastase family member 3B | 8.45E-07 | −11.10 |
| 1042779786 | PNLIP | Pancreatic lipase | 1.22E-06 | −12.04 |